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Clozaril - News Articles
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Apr 26, 2007
Psychiatric Times, NY -
SAN FRANCISCO, April 25 -- While the behavioral symptoms of autism have been treated with a wide spectrum of medications, atypical antipsychotics may be the most effective drug class.So said Lawrence D. Scahill, Ph.D., of Yale University, in a presentation here at the U.S. ... -
Apr 26, 2007
Psychiatric Times, NY -
SAN FRANCISCO, April 25 -- Atypical antipsychotic medications have improved adverse-event profiles compared with the older generation of antipsychotics, but careful attention to major side effects is still required. The overall medication plan should address the major side ... -
Thursday, April 26, 2007
Psychiatric Times, NY -
risperidone (Risperdal) or ziprasidone (Geodon) as initial treatment with olanzapine (Zyprexa) and clozapine (Clozaril) as alternate choices. Nonresponders should be put on an alternate monotherapy.Stage two, for patients who get only partial response is to try ... -
Apr 13, 2007
Genetic Engineering News (press release), NY -
Acadia’s second schizophrenia candidate is ACP-104, or N-desmethylclozapine, the major metabolite of clozapine, an atypical drug. It is being developed as a novel, stand-alone therapy. The drug combines an atypical antipsychotic efficacy profile with the potential benefit of enhanced cognition, thereby ... -
Mar 31, 2007
Radio New Zealand, New Zealand -
The Intensive Medicines Monitoring Programme says one person has died from an acute blood disorder as a result of using Clozapine. It says four other deaths were caused by another side effect, severe constipation.Pete Ellis, from the University of Otago and ... -
Apr 5, 2007
Psychiatric Services (subscription) -
OBJECTIVE: Patients with schizophrenia treated with clozapine often gain weight. This study evaluated the effects of dietary control and physical activity among obese inpatients with schizophrenia being treated with clozapine. METHODS: Fifty-three clozapine-treated obese patients with schizophrenia in a veterans ... -
Apr 12, 2007
Journal of Neuropsychiatry (subscription) -
SIR: Most of the study by Ernst and Goldberg 1 reported perinatal outcome with clozapine therapy with no focus on neurodevelopment. Here, I report a case of a woman with schizophrenia who continued clozapine treatment throughout her 9 months of ... -
Apr 5, 2007
Drug Newswire (press release), CT -
At Alamo, he created a fully integrated commercial pharmaceutical company to market Fazaclo, a reformulation of Novartis' anti-psychotic drug, Clozaril. ... -
Monday, April 16, 2007
Fresno Bee (subscription), CA -
13 and 14 Gremminger was given 300 milligrams of Clozaril. Spitz wrote that the combination of both drugs was dangerous. The doses were given despite a note in his admitting report telling doctors that Gremminger had stopped taking Clozaril for about a month before he arrived ... -
Monday, April 02, 2007
Am J Psychiatry (subscription) -
Rosenheck RA, Swartz MS, Perkins DO, Keefe RS, Davis CD, Severe J, Hsiao JK, the CATIE Investigators: Effectiveness of clozapine versus olanzapine, ...
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Mar 29, 2007
PharmaLive.com (press release), PA -
In contrast, clozapine impaired performance in both these assays. The pro-cognitive effects of ACP-104 were shown to be dependent upon M1 muscarinic activity. These findings suggest that ACP-104 will have a superior clinical profile with activity against all symptom domains (positive, ... -
Monday, April 02, 2007
Am J Psychiatry (subscription) -
To The Editor: The study by Robert A. Rosenheck, MD and colleagues represents a large and ambitious attempt to study the cost-effectiveness of pharmacotherapy for the treatment of schizophrenia (1). The authors acknowledge the caveats for policy making. However, we are concerned ... -
Monday, April 02, 2007
Am J Psychiatry (subscription) -
To The Editor: Stephen Soumerai and Michael R. Law urge appropriate caution for antipsychotic formulary policy development, but their letter implicitly endorses maintenance of the current status quo. Second-generation antipsychotics have captured 90% of the market due, in part, to ... -
Monday, April 02, 2007
Archives of General Psychiatry -
Study Selection The abstracts, titles, and index terms of studies were searched using the following key words: aripiprazole, amisulpride, clozapine, olanzapine, quetiapine, risperidone, ziprasidone, and zotepine in conjunction with mania, manic, and bipolar. Data Extraction Data on efficacy, global ... -
Mar 27, 2007
Journal of American Medical Association (subscription), IL -
"Clinically, clozapine did wonderful things, but drug companies had no idea why," said Snyder. Other AAPDs were subsequently manufactured that mimicked ... -
Mar 31, 2007
newswire.co.nz, New Zealand -
The Ministry of Health says the benefits of using of the anti-psychotic drug Clozapine outweigh the risks, despite a review showing five people have died after being prescribed the drug.The Intensive Medicines Monitoring Program says after taking the drug, one patient died from an ... -
Mar 31, 2007
Radio New Zealand, New Zealand -
Health professionals are being urged to monitor patients on a schizophrenia drug after a review found that five people have died from its side effects. The Intensive Medicines Monitoring Programme says one person has died from an acute blood disorder as a result of using ... -
Tuesday, April 03, 2007
Earthtimes.org -
At Alamo, he created a fully integrated commercial pharmaceutical company to market Fazaclo, a reformulation of Novartis' anti-psychotic drug, Clozaril. ... -
Feb 26, 2007
Globe and Mail, Canada -
A fourth in this class, clozapine (Clozaril), was not studied. But because it is in the same family, Health Canada included it in its warning about the ... -
Feb 28, 2007
Am J Psychiatry (subscription) -
Clozapine was included for patients who chose this pathway after discontinuing phase 1 due to inefficacy; all other patients received another second-generation antipsychotic. Psychosocial functioning was assessed using the Quality of Life Scale. RESULTS: Psychosocial functioning modestly improved for the ...
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